Home > Chemistry Around Us > Application of chemistry in Medicine.

Application of chemistry in Medicine.

The labels of medicines show the amounts of the different ingredents eg iron tablets may contain 200mg of iron or a painkiller may contain 500mg of paracetamol.How accurate are they?

Measuring the active ingredients in medicines can be achieved by titration and other simple laboratory techniques.But these are not reliable enough especially when working with medicines that are needed in micrograms or where an overdose might be harmful.Quality control in the pharmaceutical industry is ensured in a number of ways.The precise quantities of ingredients for any batch of medicine are measured and recorded.Then random samples from each batch are selected and tested. The tablets or other medicines are crushed if necessary and dissoved in a known solvent often methanol.This is filtered and then diluted.Standard solutions are made accurately using pure active drug to a precise concentration.Both the random samples and the standard solution are passed through a high performance liquid chromatograph (HPLC) and the quantities are compared.

HPLC is widely used to check the quantities of active ingredients in medicines.The result of this process show if the avearge content of the medicine lies within the accepted limits of variation.

About these ads
Categories: Chemistry Around Us
  1. November 5, 2009 at 5:06 PM

    This particular blogspot is more about techniques in measurement or preparation techniques for chemistry, not quite about the chemicals you encountered in daily life.

  2. rachita
    July 3, 2011 at 3:21 PM

    what was the logic behind this all give a full to example

  3. rachita
    July 3, 2011 at 3:23 PM

    what was the logic behind th

  4. rachita
    July 3, 2011 at 3:23 PM

    kya bakvas

  5. Ishaq ibrahim
    January 28, 2012 at 4:12 AM

    Is there not any gravimetric instrument we can use to subtitute for this HPLC

  6. KJK
    September 16, 2013 at 10:17 PM

    NONSENSE

  7. January 6, 2014 at 5:31 PM

    It’s truly very difficult in this busy life to listen news on Television, therefore I only use internet for that
    reason, and obtain the most recent news.

  1. No trackbacks yet.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

Follow

Get every new post delivered to your Inbox.

%d bloggers like this: